Diethyl 1,3-acetonedicarboxylate CAS NO.105-50-0

Diethyl 1,3-acetonedicarboxylate

Physicochemical properties
Colorless liquid. The boiling point is 250 ℃. Insoluble in water, soluble in alcohol, ether and benzene.
Boiling point: 250 ＆ 160; & x00b0; C (lit.)
Density: 1.113 ＆ 160; g / ml ＆ 160; at 25 ＆ 160; & x00b0; C (lit.)
Refractive index: N20 / D 1.440 (lit.)
Flash point: 187 ＆ 160; & x00b0; F
Water solubility: 10 g / L (20 & 186; c)
Application:
Organic synthesis intermediates.
For organic synthesis
The intermediate of organic synthesis and pharmaceutical synthesis can be used to synthesize strontium ranelate.

Henan Purui Pharmaceutical Co., Ltd was established in 2004 ,with fixed assets of 60 million yuan, existing staff more than 300 people is a pharmaceutical raw materials, pharmaceutical intermediates, tablets, capsules for the main products integrated backbone pharmaceutical enterprises.
Henan Purui Pharmaceutical Co., Ltd is located in Xihua County industrial Agglomeration Area of Henan Province, covers an area of 80,000 square meters. The company strictly implement the national “drug production management norms” ,is the heart and brain blood vessels, anti-tumor, new antibiotics and anti cholinergic drugs and other raw materials and intermediates of professional manufacturers, the national GMP certification enterprises. At the same time, the company has been on Clopidogrel Hydrogen Sulfate, fluconazole and other raw materials for the United States to declare the DMF file.
Henan PURUI Pharmaceutical Co., Ltd is strong in research and development. R & D center has nearly 100 experienced professional and technical personnel, has imported high-performance liquid chromatography, gas chromatography, UV spectrophotometer, infrared spectrophotometric meter, polar meter, analysis of balance, intelligent dissolution instrument, such as a large number of perfect and advanced precision instrument and equipment. Based on the markets, the company developed a variety of medicines, such as atorvastatin calcium, Clopidogrel Hydrogen Sulfate and other markets. Since its establishment, the company has the Peking University, Shanghai institute of medicine, Fudan University, Shanghai institute of medicine, Zhengzhou University medical school and other scientific research institutes to establish a long-term strategic cooperative relation. In order to expand the business, better services to customer at home and abroad, the company also established a professional marketing team in Shanghai-Le Yan medicine, committed to the global sales of raw materials and pharmaceutical intermediates.
At present, the company is undertaking to build a new second production base in Xihua, Henan national high-tech of Biological & Medicine Zone. The production base covers an area of 70,000 square meters, with a total investment of more than 100 million yuan, will be strictly in accordance with the United States CGMP standard construction. After the completion of the project, will be through the domestic GMP, the United States CGMP, the European Union CEP and other related certification.
Purui pharmaceutical adhere to the “quality first, people-oriented” management principles, “with the times, pioneering and enterprising” spirit of enterprise, in the field of medicine and continuously forge ahead. Rely on the efficient management team and professional R & D personnel and professional marketing team, Purui is striving to produce new products for the health of human life and work.